cPRA Increases With DQA, DPA, and DPB Unacceptable Antigens in the Canadian cPRA Calculator
نویسندگان
چکیده
منابع مشابه
cPRA Increases With DQA, DPA, and DPB Unacceptable Antigens in the Canadian cPRA Calculator
A calculated panel reactive antibody (cPRA) estimates the percentage of donors with unacceptable antigens (UA) for a recipient. cPRA may be underestimated in transplant candidates with UA to DQA, DPA, and DPB if these are not included in the calculation program. To serve the National Canadian Transplant Programs, a cPRA calculator was developed with complete molecular typing for all donors at H...
متن کاملApplication of Calculated Panel Reactive Antibody Using HLA Frequencies in Koreans
BACKGROUND Introduction of the Luminex panel reactive antibody (PRA)-single antigen (SA) assay has increased the detection rates of unacceptable antigens in sensitized patients; the calculated PRA (CPRA) level represents the percentage of actual organ donors that express 1 or more of these unacceptable antigens. We developed a CPRA calculator based on the HLA frequencies in Koreans to measure s...
متن کاملAssessment of Spanish Panel Reactive Antibody Calculator and Potential Usefulness
BACKGROUND AND OBJECTIVES The calculated panel reactive of antibodies (cPRAs) necessary for kidney donor-pair exchange and highly sensitized programs are estimated using different panel reactive antibody (PRA) calculators based on big enough samples in Eurotransplant (EUTR), United Network for Organ Sharing (UNOS), and Canadian Transplant Registry (CTR) websites. However, those calculators can ...
متن کاملAllocating Deceased Donor Kidneys to Candidates with High Panel-Reactive Antibodies.
BACKGROUND AND OBJECTIVES In December of 2014, the Organ Procurement and Transplant Network implemented a new Kidney Allocation System (KAS) for deceased donor transplant, with increased priority for highly sensitized candidates (calculated panel-reactive antibody [cPRA] >99%). We used a modified version of the new KAS to address issues of access and equity for these candidates. DESIGN, SETTI...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2015
ISSN: 1600-6135,1600-6143
DOI: 10.1111/ajt.13355